(مجموعه مقالات علمی و تخصصی و بروشور رکتول)

(Rectol Scientific Articles)

Myrtus communis Essential Oil for The Treatment of Hemorrhoids: A Randomized Double-Blind Double-Dummy Parallel-Group Comparative Study

The aim of this study was to evaluate the efficacy of a topical lotion prepared from M. communis essential oil of in the alleviation of hemorrhoids symptoms, and compare its effects with those of anti-hemorrhoid ointment in a randomized double-blind double-dummy trial. A total of 106 patients with hemorrhoids symptoms were recruited and randomized to receive either M. communis lotion and placebo ointment (n=50; age: 36.2±10.8) or anti-hemorrhoid ointment (containing hydrocortisone, lidocaine, aluminium subacetate and zinc oxide) and placebo lotion (n=56; age: 40.6±11.1) for a period of two weeks. The severity and frequency of hemorrhoids symptoms were evaluated at baseline and at the end of trial. All evaluated symptoms (bleeding, permanent pain, pain during defecation, anal itching and irritation, heaviness and tenesmus) were significantly decreased by the end of trial in either of the study groups (p<0.001). There was no significant difference in the improvement rate for any of the assessed symptoms between M. communis lotion and anti-hemorrhoid ointment (p>0.05). The results of this research provide the first clinical evidence on the efficacy of M. communis essential oil in the alleviation of hemorrhoids symptoms and further support the application of this plant as an anti-hemorrhoid agent in traditional medicine.



Yunes Panahi1,*, Seyed Morteza Mousavi-Nayeeni2, Amirhossein Sahebkar3, Seyyed Ahmad Fanaie2, Alireza Rahimnia2, Fatemeh Beiraghdar4

1. Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.

2. Department of Surgery, Baqiyatallah University of Medical Sciences, Tehran, Iran.

3. Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

4. Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.

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